129 research outputs found

    Assessment of the performance of X-band satellite radar data for landslide mapping and monitoring: Upper Tena Valley case study.

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    Abstract. The aim of this work is to analyse the advantages and disadvantages of using the new X-band SAR data acquired by TerraSAR-X sensors for landslides mapping. This dataset has been processed using a Persistent Scatterer Interferometry technique over the Upper Tena Valley (Central Pyrenees, Spain). In the first section, the geological and geomorphological setting of the study area is introduced, focusing on the description of the landslide inventory. Then the Stable Point Network technique is briefly described, followed by the assessment of the performance of the X-band SAR dataset. In this context, we present first a model to predict the distribution of Persistent Scatterers based on the slope geometry and the land use information, which has then been validated with X-band data results. On a second stage, we have assessed the performance of X-band dataset to detect and monitor mapped landslides. Finally some illustrative case studies are shown demonstrating the potential of using X-band SAR data not only for landslide mapping but also to detect and monitor deformations affecting human infrastructures

    Semi-automatic mapping of shallow landslides using free Sentinel-2 images and Google Earth Engine

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    The global availability of Sentinel-2 data and the widespread coverage of cost-free and high-resolution images nowadays give opportunities to map, at a low cost, shallow landslides triggered by extreme events (e.g. rainfall, earthquakes). Rapid and low-cost shallow landslide mapping could improve damage estimations, susceptibility models and land management. This work presents a two-phase procedure to detect and map shallow landslides. The first is a semi-automatic methodology allowing for mapping potential shallow landslides (PLs) using Sentinel-2 images. The PL aims to detect the most affected areas and to focus on them an high-resolution mapping and further investigations. We create a GIS-based and user-friendly methodology to extract PL based on pre- and post-event normalised difference vegetation index (NDVI) variation and geomorphological filtering. In the second phase, the semi-automatic inventory was compared with a benchmark landslide inventory drawn on high-resolution images. We also used Google Earth Engine scripts to extract the NDVI time series and to make a multi-temporal analysis. We apply this procedure to two study areas in NW Italy, hit in 2016 and 2019 by extreme rainfall events. The results show that the semi-automatic mapping based on Sentinel-2 allows for detecting the majority of shallow landslides larger than satellite ground pixel (100 m2). PL density and distribution match well with the benchmark. However, the false positives (30 % to 50 % of cases) are challenging to filter, especially when they correspond to riverbank erosions or cultivated land.</p

    Az előszerződés, mint a jövőbeli ismételt foglalkoztatás jogi keretbe foglalt ígérete

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    Abstract: In this paper a methodology is proposed to elaborate landslide activity maps through the use of PS (Persistent Scatterer) data. This is illustrated through the case study of Tramuntana Range in the island of Majorca (Spain), where ALOS (Advanced Land Observing Satellite) images have been processed through a Persistent Scatterer Interferometry (PSI) technique during the period of 2007–2010. The landslide activity map provides, for every monitored landslide, an assessment of the PS visibility according to the relief, land use, and satellite acquisition parameters. Landslide displacement measurements are projected along the steepest slope, in order to compare landslide velocities with different slope orientations. Additionally, a ground motion activity map is also generated, based on active PS clusters not included within any known landslide phenomenon, butRemote Sens. 2013, 5 6199 even moving, potentially referred to unmapped landslides or triggered by other kinds o

    Application of multi-sensor advanced DInSAR analysis to severe land subsidence recognition: Alto Guadalentín Basin (Spain)

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    Multi-sensor advanced DInSAR analyses have been performed and compared with two GPS station measurements, in order to evaluate the land subsidence evolution in a 20-year period, in the Alto Guadalentín Basin where the highest rate of man-induced subsidence (> 10 cm yr&minus;1) of Europe had been detected. The control mechanisms have been examined comparing the advanced DInSAR data with conditioning and triggering factors (i.e. isobaths of Plio-Quaternary deposits, soft soil thickness and piezometric level)

    Mechanisms of Resistance to Noncovalent Bruton's Tyrosine Kinase Inhibitors

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    Background Covalent (irreversible) Bruton's tyrosine kinase (BTK) inhibitors have transformed the treatment of multiple B-cell cancers, especially chronic lymphocytic leukemia (CLL). However, resistance can arise through multiple mechanisms, including acquired mutations in BTK at residue C481, the binding site of covalent BTK inhibitors. Noncovalent (reversible) BTK inhibitors overcome this mechanism and other sources of resistance, but the mechanisms of resistance to these therapies are currently not well understood. Methods We performed genomic analyses of pretreatment specimens as well as specimens obtained at the time of disease progression from patients with CLL who had been treated with the noncovalent BTK inhibitor pirtobrutinib. Structural modeling, BTK-binding assays, and cell-based assays were conducted to study mutations that confer resistance to noncovalent BTK inhibitors. Results Among 55 treated patients, we identified 9 patients with relapsed or refractory CLL and acquired mechanisms of genetic resistance to pirtobrutinib. We found mutations (V416L, A428D, M437R, T474I, and L528W) that were clustered in the kinase domain of BTK and that conferred resistance to both noncovalent BTK inhibitors and certain covalent BTK inhibitors. Mutations in BTK or phospholipase C gamma 2 (PLCγ2), a signaling molecule and downstream substrate of BTK, were found in all 9 patients. Transcriptional activation reflecting B-cell-receptor signaling persisted despite continued therapy with noncovalent BTK inhibitors.Conclusions Resistance to noncovalent BTK inhibitors arose through on-target BTK mutations and downstream PLCγ2 mutations that allowed escape from BTK inhibition. A proportion of these mutations also conferred resistance across clinically approved covalent BTK inhibitors. These data suggested new mechanisms of genomic escape from established covalent and novel noncovalent BTK inhibitors. (Funded by the American Society of Hematology and others.

    Characterization of arsenic content in marine organisms from temperate, tropical and polar environments.

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